The effect of various levels of inclusion of Cola notida meal on growth performance and hematological parameters of Clarias gariepinus was investigated for 56 days. Fingerlings of C. gariepinus (6.57g + 0.06) were stocked in 10 hapas at the rate of 20 fingerlings per hapas. Iso-nitrogenous and iso-caloric diets were formulated with inclusion levels of white kola meal at 0, 50, 100, 150, and 200gkg-1. The result obtained showed that fish fed 200gkg-1 gave the highest weight gain of 17.92g followed by fish fed with 150g/kg white kola meal (16.49g). The least mean weight gain was recorded in the control diet with 0% kola inclusion. The same trend were observed for specific growth rate, Protein efficiency rates and food conversion ratio (P<0.05). Hence, to optimize the growth of Clarias gariepinus, Cola notida can be included up to 200gkg-1.